Direct Protein Interactions Are Responsible for Ikaros-GATA and Ikaros-Cdk9 Cooperativeness in Hematopoietic Cells

Ikaros (Ik) is a critical regulator of hematopoietic gene expression. Here, we established that the Ik interactions with GATA transcription factors and cyclin-dependent kinase 9 (Cdk9), a component of the positive transcription elongation factor b (P-TEFb), are required for transcriptional activatio...

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Bibliographic Details
Main Authors: Bottardi, Stefania, Mavoungou, Lionel, Bourgoin, Vincent, Mashtalir, Nazar, Affar, El Bachir, Milot, Eric
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753914/
https://ncbi.nlm.nih.gov/pubmed/23732910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00296-13
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