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Role of Membrane Association and Atg14-Dependent Phosphorylation in Beclin-1-Mediated Autophagy
During autophagy, a double membrane envelops cellular material for trafficking to the lysosome. Human beclin-1 and its yeast homologue, Atg6/Vps30, are scaffold proteins bound in a lipid kinase complex with multiple cellular functions, including autophagy. Several different Atg6 complexes exist, wit...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753860/ https://ncbi.nlm.nih.gov/pubmed/23878393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00079-13 |
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