Role of Membrane Association and Atg14-Dependent Phosphorylation in Beclin-1-Mediated Autophagy

During autophagy, a double membrane envelops cellular material for trafficking to the lysosome. Human beclin-1 and its yeast homologue, Atg6/Vps30, are scaffold proteins bound in a lipid kinase complex with multiple cellular functions, including autophagy. Several different Atg6 complexes exist, wit...

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Detalhes bibliográficos
Main Authors: Fogel, Adam I., Dlouhy, Brian J., Wang, Chunxin, Ryu, Seung-Wook, Neutzner, Albert, Hasson, Samuel A., Sideris, Dionisia P., Abeliovich, Hagai, Youle, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753860/
https://ncbi.nlm.nih.gov/pubmed/23878393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00079-13
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