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Does transcription factor induced pluripotency accurately mimic embryo derived pluripotency?

When Takahashi and Yamanaka first demonstrated that just four transcription factors could reprogram a fibroblast to a pluripotent stem cell, the first wave of data to emerge focused on how similar these induced pluripotent stem cells (iPSCs) were to embryo-derived pluripotent stem cells (ESCs) [1]....

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Hlavní autor: Lowry, WE
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753773/
https://ncbi.nlm.nih.gov/pubmed/23079387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2012.07.003
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