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Does transcription factor induced pluripotency accurately mimic embryo derived pluripotency?
When Takahashi and Yamanaka first demonstrated that just four transcription factors could reprogram a fibroblast to a pluripotent stem cell, the first wave of data to emerge focused on how similar these induced pluripotent stem cells (iPSCs) were to embryo-derived pluripotent stem cells (ESCs) [1]....
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753773/ https://ncbi.nlm.nih.gov/pubmed/23079387 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2012.07.003 |
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