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Nucleosome Dynamics as Modular Systems that Integrate DNA Damage and Repair

By some estimates, a eukaryotic cell must repair up to 10,000 DNA lesions per cell cycle to counteract endogenous sources of DNA damage. Exposure to environmental toxins, UV sources, or other radiations only increases this enormous number. Failure to repair such lesions can lead to a deleterious mut...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Peterson, Craig L., Almouzni, Genevieve
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753706/
https://ncbi.nlm.nih.gov/pubmed/24003210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a012658
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