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Nucleosome Dynamics as Modular Systems that Integrate DNA Damage and Repair
By some estimates, a eukaryotic cell must repair up to 10,000 DNA lesions per cell cycle to counteract endogenous sources of DNA damage. Exposure to environmental toxins, UV sources, or other radiations only increases this enormous number. Failure to repair such lesions can lead to a deleterious mut...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753706/ https://ncbi.nlm.nih.gov/pubmed/24003210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a012658 |
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