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Nucleosome Dynamics as Modular Systems that Integrate DNA Damage and Repair

By some estimates, a eukaryotic cell must repair up to 10,000 DNA lesions per cell cycle to counteract endogenous sources of DNA damage. Exposure to environmental toxins, UV sources, or other radiations only increases this enormous number. Failure to repair such lesions can lead to a deleterious mut...

詳細記述

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書誌詳細
主要な著者: Peterson, Craig L., Almouzni, Genevieve
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753706/
https://ncbi.nlm.nih.gov/pubmed/24003210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a012658
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