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Structure-function analysis of the 5′ end of yeast U1 snRNA highlights genetic interactions with the Msl5•Mud2 branchpoint-binding complex and other spliceosome assembly factors

Yeast pre-mRNA splicing initiates via formation of a complex comprising U1 snRNP bound at the 5′ splice site (5′SS) and the Msl5•Mud2 heterodimer engaged at the branchpoint (BP). Here, we present a mutational analysis of the U1 snRNA, which shows that although enlarging the 5′ leader between the TMG...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Schwer, Beate, Chang, Jonathan, Shuman, Stewart
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2013
विषय:
RNA
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753624/
https://ncbi.nlm.nih.gov/pubmed/23754852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt490
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