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Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels
Kv11.1 channels are critical for the maintenance of a normal heart rhythm. The flow of potassium ions through these channels is controlled by two voltage-regulated gates, termed “activation” and “inactivation,” located at opposite ends of the pore. Crucially in Kv11.1 channels, inactivation gating o...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3753607/ https://ncbi.nlm.nih.gov/pubmed/23980196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201310975 |
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