A gating charge interaction required for late slow inactivation of the bacterial sodium channel NavAb

Voltage-gated sodium channels undergo slow inactivation during repetitive depolarizations, which controls the frequency and duration of bursts of action potentials and prevents excitotoxic cell death. Although homotetrameric bacterial sodium channels lack the intracellular linker-connecting homologo...

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Bibliographic Details
Main Authors: Gamal El-Din, Tamer M., Martinez, Gilbert Q., Payandeh, Jian, Scheuer, Todd, Catterall, William A.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2013
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753604/
https://ncbi.nlm.nih.gov/pubmed/23980192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201311012
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