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Functional K(Ca)3.1 channels regulate steroid insensitivity in bronchial smooth muscle cells

Identifying the factors responsible for relative glucocorticosteroid (GC) resistance present in patients with severe asthma and finding tools to reverse it are of paramount importance. In asthma there is in vivo evidence of GC-resistant pathways in airway smooth muscle (ASM) bundles which can be mod...

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Autores principales: Chachi, Latifa, Shikotra, Aarti, Duffy, S. Mark, Tliba, Omar, Brightling, Christopher, Bradding, Peter, Amrani, Yassine
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753579/
https://ncbi.nlm.nih.gov/pubmed/23904164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300104
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