Bmp7 Maintains Undifferentiated Kidney Progenitor Population and Determines Nephron Numbers at Birth

The number of nephrons, the functional units of the kidney, varies among individuals. A low nephron number at birth is associated with a risk of hypertension and the progression of renal insufficiency. The molecular mechanisms determining nephron number during embryogenesis have not yet been clarifi...

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Autors principals: Tomita, Mayumi, Asada, Misako, Asada, Nariaki, Nakamura, Jin, Oguchi, Akiko, Higashi, Atsuko Y., Endo, Shuichiro, Robertson, Elizabeth, Kimura, Takeshi, Kita, Toru, Economides, Aris N., Kreidberg, Jordan, Yanagita, Motoko
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753328/
https://ncbi.nlm.nih.gov/pubmed/23991197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073554
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