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Antiretroviral Spermicide WHI-07 Prevents Vaginal and Rectal Transmission of Feline Immunodeficiency Virus in Domestic Cats

WHI-07 [5-bromo-6-methoxy-5,6-dihydro-3′-azidothymidine-5′-(p-bromophenyl)-methoxy alaninyl phosphate] is a novel dual-function aryl phosphate derivative of zidovudine with potent anti-human immunodeficiency virus (HIV) and spermicidal activities. WHI-07 was active against the feline immunodeficienc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: D'Cruz, Osmond J., Waurzyniak, Barbara, Uckun, Fatih M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC375320/
https://ncbi.nlm.nih.gov/pubmed/15047505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1082-1088.2004
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