In Vivo Toxicity, Pharmacokinetics, and Anti-Human Immunodeficiency Virus Activity of Stavudine-5′-(p-Bromophenyl Methoxyalaninyl Phosphate) (Stampidine) in Mice

We have evaluated the clinical potential of stavudine-5′-(p-bromophenyl methoxyalaninyl phosphate(stampidine [STAMP]), a novel aryl phosphate derivative of stavudine, as a new anti-human immunodeficiency virus (anti-HIV) agent, by examining its acute, subacute, and chronic toxicity profile in mice a...

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Detalhes bibliográficos
Main Authors: Uckun, Fatih M., Qazi, Sanjive, Pendergrass, Sharon, Lisowski, Elizabeth, Waurzyniak, Barbara, Chen, Chun-Lin, Venkatachalam, T. K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128716/
https://ncbi.nlm.nih.gov/pubmed/12384347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.11.3428-3436.2002
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