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In Vivo Toxicity, Pharmacokinetics, and Anti-Human Immunodeficiency Virus Activity of Stavudine-5′-(p-Bromophenyl Methoxyalaninyl Phosphate) (Stampidine) in Mice

We have evaluated the clinical potential of stavudine-5′-(p-bromophenyl methoxyalaninyl phosphate(stampidine [STAMP]), a novel aryl phosphate derivative of stavudine, as a new anti-human immunodeficiency virus (anti-HIV) agent, by examining its acute, subacute, and chronic toxicity profile in mice a...

Celý popis

Uloženo v:
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Uckun, Fatih M., Qazi, Sanjive, Pendergrass, Sharon, Lisowski, Elizabeth, Waurzyniak, Barbara, Chen, Chun-Lin, Venkatachalam, T. K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2002
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128716/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12384347/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.11.3428-3436.2002
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