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Over-expression of HSP70 attenuates caspase-dependent and caspase independent pathways and inhibits neuronal apoptosis

HSP70 is a member of the family of heat-shock proteins that are known to be up-regulated in neurons following injury and/ or stress. HSP70 over-expression has been linked to neuroprotection in multiple models, including neurodegenerative disorders. In contrast, less is known about the neuroprotectiv...

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Hlavní autoři: Sabirzhanov, Boris, Stoica, Bogdan A., Hanscom, Marie, Piao, Chun-Shu, Faden, Alan I.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753080/
https://ncbi.nlm.nih.gov/pubmed/22909049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07927.x
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