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Mithramycin selectively attenuates DNA-damage-induced neuronal cell death
DNA damage triggers cell death mechanisms contributing to neuronal loss and cognitive decline in neurological disorders, including traumatic brain injury (TBI), and as a side effect of chemotherapy. Mithramycin, which competitively targets chromatin-binding sites of specificity protein 1 (Sp1), was...
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| Publicado no: | Cell Death Dis |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7385624/ https://ncbi.nlm.nih.gov/pubmed/32719328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02774-6 |
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