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Mapping pilicide anti-virulence effect in Escherichia coli, a comprehensive structure–activity study

Pilicides prevent pili formation and thereby the development of bacterial biofilms in Escherichia coli. We have performed a comprehensive structure activity relationship (SAR) study of the dihydrothiazolo ring-fused 2-pyridone pilicide central fragment by varying all open positions. Orthogonal proje...

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Detalhes bibliográficos
Main Authors: Chorell, Erik, Pinkner, Jerome S., Bengtsson, Christoffer, Banchelin, Thomas Sainte-Luce, Edvinsson, Sofie, Linusson, Anna, Hultgren, Scott J., Almqvist, Fredrik
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753005/
https://ncbi.nlm.nih.gov/pubmed/22464688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.01.048
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