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Synthesis and application of a bromomethyl substituted scaffold to be used for efficient optimization of anti-virulence activity
Pilicides are a class of compounds that attenuate virulence in Gram negative bacteria by blocking the chaperone/usher pathway in Escherichia coli. It has also been shown that compounds derived from the peptidomimetic scaffold that the pilicides are based on can prevent both Aβ aggregation and curli...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3694777/ https://ncbi.nlm.nih.gov/pubmed/21316127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2011.01.025 |
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