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MiR-28 regulates Nrf2 expression through a Keap1-independent mechanism
NF-E2-related factor 2 (Nrf2) is an important transcription factor involved in antioxidant response. Nrf2 binds antioxidant response elements (ARE) within promoters of genes encoding detoxification enzymes (e.g., NAD (P) H-quinone oxidoreductase 1 (NQO1)) leading to their transcriptional activation....
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3752913/ https://ncbi.nlm.nih.gov/pubmed/21638050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-011-1604-1 |
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