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Regulations of Gene Expression in Medullary Thymic Epithelial Cells Required for Preventing the Onset of Autoimmune Diseases

Elimination of potential self-reactive T cells in the thymus is crucial for preventing the onset of autoimmune diseases. Epithelial cell subsets localized in thymic medulla [medullary thymic epithelial cells (mTECs)] contribute to this process by supplying a wide range of self-antigens that are othe...

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Détails bibliographiques
Auteurs principaux: Akiyama, Taishin, Shinzawa, Miho, Qin, Junwen, Akiyama, Nobuko
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752772/
https://ncbi.nlm.nih.gov/pubmed/23986760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00249
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