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Common corruption of the mTOR signaling network in human tumors

The mammalian Target of Rapamycin (mTOR) is responsive to numerous extracellular and intracellular cues and, through the formation of two physically and functionally distinct complexes, plays a central role in the homeostatic control of cell growth, proliferation and survival. Through aberrant activ...

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Bibliografske podrobnosti
Main Authors: Menon, Suchithra, Manning, Brendan D.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752670/
https://ncbi.nlm.nih.gov/pubmed/19956179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.352
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