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Common corruption of the mTOR signaling network in human tumors
The mammalian Target of Rapamycin (mTOR) is responsive to numerous extracellular and intracellular cues and, through the formation of two physically and functionally distinct complexes, plays a central role in the homeostatic control of cell growth, proliferation and survival. Through aberrant activ...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3752670/ https://ncbi.nlm.nih.gov/pubmed/19956179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.352 |
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