Efficacy, Safety, and Plasma Pharmacokinetics of Escalating Dosages of Intravenously Administered Ravuconazole Lysine Phosphoester for Treatment of Experimental Pulmonary Aspergillosis in Persistently Neutropenic Rabbits

Ravuconazole is a new antifungal triazole with broad-spectrum activity and a long half-life in plasma. We studied the antifungal efficacy, safety, and pharmacokinetics of ravuconazole lysine phosphoester in escalating dosages for the treatment of invasive pulmonary aspergillosis due to Aspergillus f...

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Hauptverfasser: Petraitiene, Ruta, Petraitis, Vidmantas, Lyman, Caron A., Groll, Andreas H., Mickiene, Diana, Peter, Joanne, Bacher, John, Roussillon, Kristin, Hemmings, Melissa, Armstrong, Derrek, Avila, Nilo A., Walsh, Thomas J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC375262/
https://ncbi.nlm.nih.gov/pubmed/15047519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1188-1196.2004
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