Caspofungin Resistance in Candida albicans: Correlating Clinical Outcome with Laboratory Susceptibility Testing of Three Isogenic Isolates Serially Obtained from a Patient with Progressive Candida Esophagitis

A patient with azole-refractory thrush-esophagitis responded initially to caspofungin, but the treatment eventually failed. In a murine model, caspofungin was effective against two early isolates for which the MICs of caspofungin were low, but it was less effective against a late isolate for which t...

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Detalhes bibliográficos
Main Authors: Hernandez, Steve, López-Ribot, José L., Najvar, Laura K., McCarthy, Dora I., Bocanegra, Rosie, Graybill, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC375251/
https://ncbi.nlm.nih.gov/pubmed/15047549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1382-1383.2004
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