Efficacy and Pharmacokinetics of Intravenous Nanocapsule Formulations of Halofantrine in Plasmodium berghei-Infected Mice

The efficacy and pharmacokinetics of a new parenteral formulation of halofantrine were studied in mice infected with Plasmodium berghei. The formulation consisted of nanocapsules with an oily core, prepared from either poly(d,l-lactide) (PLA) homopolymer or PLA that was surface modified with grafted...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Mosqueira, Vanessa C. F., Loiseau, Philippe M., Bories, Christian, Legrand, Philippe, Devissaguet, Jean-Philippe, Barratt, Gillian
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2004
נושאים:
Experimental Therapeutics
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC375247/
https://ncbi.nlm.nih.gov/pubmed/15047523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1222-1228.2004
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