Design and Antileishmanial Activity of Amphotericin B-Loaded Stable Ionic Amphiphile Biovector Formulations

A new delivery system, Ionic Amphiphilic Biovector (ABV), comprised of anionic lipids (dipalmitoyl phosphatidyl glycerol) included in a cationic cross-linked polysaccharide matrix was used as a reservoir for amphotericin B (AmB). Two ABV formulations exhibited an in vitro and in vivo efficacy simila...

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Autors principals: Loiseau, P. M., Imbertie, L., Bories, C., Betbeder, D., De Miguel, I.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC127191/
https://ncbi.nlm.nih.gov/pubmed/11959611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1597-1601.2002
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