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Tumour necrosis factor-α-induced loss of intestinal barrier function requires TNFR1 and TNFR2 signalling in a mouse model of total parenteral nutrition

Tumour necrosis factor-α (TNF-α) has been reported to play a central role in intestinal barrier dysfunction in many diseases; however, the precise role of the TNF-α receptors (TNFRs) has not been well defined using in vivo models. Our previous data showed that enteral nutrient deprivation or total p...

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Autori principali: Feng, Yongjia, Teitelbaum, Daniel H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752452/
https://ncbi.nlm.nih.gov/pubmed/23753529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.253518
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