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Glutamate prevents intestinal atrophy via luminal nutrient sensing in a mouse model of total parenteral nutrition

Small intestine luminal nutrient sensing may be crucial for modulating physiological functions. However, its mechanism of action is incompletely understood. We used a model of enteral nutrient deprivation, or total parenteral nutrition (TPN), resulting in intestinal mucosal atrophy and decreased epi...

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Detalhes bibliográficos
Main Authors: Xiao, Weidong, Feng, Yongjia, Holst, Jens J., Hartmann, Bolette, Yang, Hua, Teitelbaum, Daniel H.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986837/
https://ncbi.nlm.nih.gov/pubmed/24497581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.13-238311
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