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Dissociation of E-cadherin and β-catenin in a mouse model of total parenteral nutrition: a mechanism for the loss of epithelial cell proliferation and villus atrophy

Total parenteral nutrition (TPN) leads a loss of epithelial barrier function, decline in epithelial cell (EC) proliferation, and decreased expression of E-cadherin. As a large portion of intracellular β-catenin is tightly associated with E-cadherin, we hypothesized that the loss of E-cadherin would...

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Detalhes bibliográficos
Main Authors: Feng, Yongjia, Sun, Xiaoyi, Yang, Hua, Teitelbaum, Daniel H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670086/
https://ncbi.nlm.nih.gov/pubmed/19064618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.162719
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