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A combination of directing groups and chiral anion phase-transfer catalysis for enantioselective fluorination of alkenes

We report a catalytic enantioselective electrophilic fluorination of alkenes to form tertiary and quaternary C(sp3)-F bonds and generate β-amino- and β-aryl-allylic fluorides. The reaction takes advantage of the ability of chiral phosphate anions to serve as solid–liquid phase transfer catalysts and...

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Detalhes bibliográficos
Main Authors: Wu, Jeffrey, Wang, Yi-Ming, Drljevic, Amela, Rauniyar, Vivek, Phipps, Robert J., Toste, F. Dean
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752255/
https://ncbi.nlm.nih.gov/pubmed/23922394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304346110
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