Unifying model for molecular determinants of the preselection Vβ repertoire

The primary antigen receptor repertoire is sculpted by the process of V(D)J recombination, which must strike a balance between diversification and favoring gene segments with specialized functions. The precise determinants of how often gene segments are chosen to complete variable region coding exon...

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Detalhes bibliográficos
Main Authors: Gopalakrishnan, Suhasni, Majumder, Kinjal, Predeus, Alexander, Huang, Yue, Koues, Olivia I., Verma-Gaur, Jiyoti, Loguercio, Salvatore, Su, Andrew I., Feeney, Ann J., Artyomov, Maxim N., Oltz, Eugene M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752219/
https://ncbi.nlm.nih.gov/pubmed/23918392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304048110
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