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THE ROLE OF MULTIDRUG RESISTANCE ASSOCIATED PROTEIN (MRP) IN THE BLOOD-BRAIN BARRIER AND OPIOID ANALGESIA

The blood brain barrier protects the brain from circulating compounds and drugs. The ATP-binding cassette (ABC) transporter P-glycoprotein (Pgp) is involved with the barrier, both preventing the influx of agent from the blood into the brain and facilitating the efflux of compounds from the brain int...

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Bibliografische gegevens
Hoofdauteurs: Su, Wendy, Pasternak, Gavril W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752163/
https://ncbi.nlm.nih.gov/pubmed/23508590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.21667
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