Antibody-Aided Clearance of Extracellular α-Synuclein Prevents Cell-to-Cell Aggregate Transmission

Abnormal deposition and intercellular propagation of α-synuclein plays a central role in the pathogenesis of disorders such as Parkinson's Disease (PD) and dementia with Lewy bodies (DLB). Previous studies demonstrated that immunization against α-synuclein resulted in reduced α-synuclein accumu...

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Detalhes bibliográficos
Main Authors: Bae, Eun-Jin, Lee, He-Jin, Rockenstein, Edward, Ho, Dong-Hwan, Park, Eun-Bi, Yang, Na-Young, Desplats, Paula, Masliah, Eliezer, Lee, Seung-Jae
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752153/
https://ncbi.nlm.nih.gov/pubmed/23015436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1292-12.2012
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