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The Arginine-Rich RNA-Binding Motif of HIV-1 Rev Is Intrinsically Disordered and Folds upon RRE Binding

Arginine-rich motifs (ARMs) capable of binding diverse RNA structures play critical roles in transcription, translation, RNA trafficking, and RNA packaging. The regulatory HIV-1 protein Rev is essential for viral replication and belongs to the ARM family of RNA-binding proteins. During the early sta...

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Detalhes bibliográficos
Main Authors: Casu, Fabio, Duggan, Brendan M., Hennig, Mirko
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752131/
https://ncbi.nlm.nih.gov/pubmed/23972852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.07.022
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