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Analysis of the EIAV Rev-Responsive Element (RRE) Reveals a Conserved RNA Motif Required for High Affinity Rev Binding in Both HIV-1 and EIAV

A cis-acting RNA regulatory element, the Rev-responsive element (RRE), has essential roles in replication of lentiviruses, including human immunodeficiency virus (HIV-1) and equine infection anemia virus (EIAV). The RRE binds the viral trans-acting regulatory protein, Rev, to mediate nucleocytoplasm...

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Detalles Bibliográficos
Main Authors: Lee, Jae-Hyung, Culver, Gloria, Carpenter, Susan, Dobbs, Drena
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386976/
https://ncbi.nlm.nih.gov/pubmed/18523581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002272
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