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How Robust Is the Mechanism of Folding-Upon-Binding for an Intrinsically Disordered Protein?

The mechanism of interaction of an intrinsically disordered protein (IDP) with its physiological partner is characterized by a disorder-to-order transition in which a recognition and a binding step take place. Even if the mechanism is quite complex, IDPs tend to bind their partner in a cooperative m...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Bonetti, Daniela, Troilo, Francesca, Brunori, Maurizio, Longhi, Sonia, Gianni, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937165/
https://ncbi.nlm.nih.gov/pubmed/29694866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.03.017
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