Targeting the Overproduction of Peroxynitrite for the Prevention and Reversal of Paclitaxel-Induced Neuropathic Pain

Chemotherapy-induced peripheral neuropathy (CIPN) accompanied by chronic neuropathic pain is a major dose-limiting side effect of a large number of antitumoral agents including paclitaxel (Taxol). Thus, CIPN is one of most common causes of dose reduction and discontinuation of what is otherwise a li...

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Autori principali: Doyle, Timothy, Chen, Zhoumou, Muscoli, Carolina, Bryant, Leesa, Esposito, Emanuela, Cuzzocrea, Salvatore, Dagostino, Concetta, Ryerse, Jan, Rausaria, Smita, Kamadulski, Andrew, Neumann, William L., Salvemini, Daniela
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752044/
https://ncbi.nlm.nih.gov/pubmed/22553021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6343-11.2012
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