Longitudinal transcriptomic dysregulation in the peripheral blood of transgenic Huntington’s disease monkeys

BACKGROUND: Huntington’s Disease (HD) is a progressive neurodegenerative disorder caused by an expansion in the polyglutamine (polyQ) region of the Huntingtin (HTT) gene. The clinical features of HD are characterized by cognitive, psychological, and motor deficits. Molecular instability, a core comp...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kocerha, Jannet, Liu, Yuhong, Willoughby, David, Chidamparam, Kumaravel, Benito, Joseph, Nelson, Kate, Xu, Yan, Chi, Tim, Engelhardt, Heidi, Moran, Sean, Yang, Shang-Hsun, Li, Shi-Hua, Li, Xiao-Jiang, Larkin, Katherine, Neumann, Adam, Banta, Heather, Yang, Jin Jing, Chan, Anthony WS
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751855/
https://ncbi.nlm.nih.gov/pubmed/23957861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-14-88
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