Longitudinal transcriptomic dysregulation in the peripheral blood of transgenic Huntington’s disease monkeys

BACKGROUND: Huntington’s Disease (HD) is a progressive neurodegenerative disorder caused by an expansion in the polyglutamine (polyQ) region of the Huntingtin (HTT) gene. The clinical features of HD are characterized by cognitive, psychological, and motor deficits. Molecular instability, a core comp...

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Detalhes bibliográficos
Main Authors: Kocerha, Jannet, Liu, Yuhong, Willoughby, David, Chidamparam, Kumaravel, Benito, Joseph, Nelson, Kate, Xu, Yan, Chi, Tim, Engelhardt, Heidi, Moran, Sean, Yang, Shang-Hsun, Li, Shi-Hua, Li, Xiao-Jiang, Larkin, Katherine, Neumann, Adam, Banta, Heather, Yang, Jin Jing, Chan, Anthony WS
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751855/
https://ncbi.nlm.nih.gov/pubmed/23957861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-14-88
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