Longitudinal transcriptomic dysregulation in the peripheral blood of transgenic Huntington’s disease monkeys

BACKGROUND: Huntington’s Disease (HD) is a progressive neurodegenerative disorder caused by an expansion in the polyglutamine (polyQ) region of the Huntingtin (HTT) gene. The clinical features of HD are characterized by cognitive, psychological, and motor deficits. Molecular instability, a core comp...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Kocerha, Jannet, Liu, Yuhong, Willoughby, David, Chidamparam, Kumaravel, Benito, Joseph, Nelson, Kate, Xu, Yan, Chi, Tim, Engelhardt, Heidi, Moran, Sean, Yang, Shang-Hsun, Li, Shi-Hua, Li, Xiao-Jiang, Larkin, Katherine, Neumann, Adam, Banta, Heather, Yang, Jin Jing, Chan, Anthony WS
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751855/
https://ncbi.nlm.nih.gov/pubmed/23957861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-14-88
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk