Intraspleen Delivery of a DNA Vaccine Coding for Superoxide Dismutase (SOD) of Brucella abortus Induces SOD-Specific CD4(+) and CD8(+) T Cells

In the development of vaccines capable of providing immunity against brucellosis, Cu-Zn superoxide dismutase (SOD) has been demonstrated to be one of the protective immunogens of Brucella abortus. In an earlier study, we provided strong evidence that intramuscular injection with a plasmid DNA carryi...

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Bibliografiske detaljer
Main Authors: Muñoz-Montesino, Carola, Andrews, Edilia, Rivers, Rodolfo, González-Smith, Andrés, Moraga-Cid, Gustavo, Folch, Hugo, Céspedes, Sandra, Oñate, Angel A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC375181/
https://ncbi.nlm.nih.gov/pubmed/15039330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.4.2081-2087.2004
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