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An RNA Vaccine Based on Recombinant Semliki Forest Virus Particles Expressing the Cu,Zn Superoxide Dismutase Protein of Brucella abortus Induces Protective Immunity in BALB/c Mice

We constructed infectious but replication-deficient Semliki Forest virus (SFV) particles carrying recombinant RNA encoding Brucella abortus Cu,Zn superoxide dismutase (SOD). The recombinant SFV particles (SFV-SOD particles) were then evaluated for their ability to induce a T-cell immune response and...

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Библиографические подробности
Главные авторы: Oñate, Angel A., Donoso, Gabriel, Moraga-Cid, Gustavo, Folch, Hugo, Céspedes, Sandra, Andrews, Edilia
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1111843/
https://ncbi.nlm.nih.gov/pubmed/15908354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.6.3294-3300.2005
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