A DNA Vaccine Encoding Cu,Zn Superoxide Dismutase of Brucella abortus Induces Protective Immunity in BALB/c Mice

This study was conducted to evaluate the immunogenicity and protective efficacy of a DNA vaccine encoding Brucella abortus Cu,Zn superoxide dismutase (SOD). Intramuscular injection of plasmid DNA carrying the SOD gene (pcDNA-SOD) into BALB/c mice elicited both humoral and cellular immune responses....

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Détails bibliographiques
Auteurs principaux: Oñate, Angel A., Céspedes, Sandra, Cabrera, Alex, Rivers, Rodolfo, González, Andrés, Muñoz, Carola, Folch, Hugo, Andrews, Edilia
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2003
Sujets:
Microbial Immunity and Vaccines
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC187304/
https://ncbi.nlm.nih.gov/pubmed/12933826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.9.4857-4861.2003
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