Deletion of wboA Enhances Activation of the Lectin Pathway of Complement in Brucella abortus and Brucella melitensis

Brucella spp. are gram-negative intracellular pathogens that survive and multiply within phagocytic cells of their hosts. Smooth organisms present O polysaccharides (OPS) on their surface. These OPS help the bacteria avoid the bactericidal action of serum. The wboA gene, coding for the enzyme glycos...

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Main Authors: Fernandez-Prada, Carmen M., Nikolich, Mikeljon, Vemulapalli, Ramesh, Sriranganathan, Nammalwar, Boyle, Stephen M., Schurig, Gerhardt G., Hadfield, Ted L., Hoover, David L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Host Response and Inflammation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC98513/
https://ncbi.nlm.nih.gov/pubmed/11401980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.7.4407-4416.2001
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