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A DNA Vaccine Encoding Cu,Zn Superoxide Dismutase of Brucella abortus Induces Protective Immunity in BALB/c Mice

This study was conducted to evaluate the immunogenicity and protective efficacy of a DNA vaccine encoding Brucella abortus Cu,Zn superoxide dismutase (SOD). Intramuscular injection of plasmid DNA carrying the SOD gene (pcDNA-SOD) into BALB/c mice elicited both humoral and cellular immune responses....

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Oñate, Angel A., Céspedes, Sandra, Cabrera, Alex, Rivers, Rodolfo, González, Andrés, Muñoz, Carola, Folch, Hugo, Andrews, Edilia
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2003
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187304/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12933826/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.9.4857-4861.2003
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