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Gambogic acid moderates cardiac responses to chronic hypoxia likely by acting on the proteasome and NF-κB pathway

Gambogic acid (GA) is the principal active ingredient of gamboges. GA was reported to exert anti-tumor and anti-inflammatory effects both in vitro and in vivo. Previously, we have shown that GA is a more tissue-specific proteasome inhibitor than bortezomib and it is less toxic to peripheral white bl...

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Main Authors:	Zhao, Canguo, Liu, Shouting, Yang, Changshan, Li, Xiaofen, Huang, Hongbiao, Liu, Ningning, Li, Shujue, Wang, Xuejun, Liu, Jinbao
Format:	Artigo
Jezik:	Inglês
Izdano:	e-Century Publishing Corporation 2013
Teme:	Original Article
Online dostop:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3751679/ https://ncbi.nlm.nih.gov/pubmed/23991348
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Gambogic acid moderates cardiac responses to chronic hypoxia likely by acting on the proteasome and NF-κB pathway

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