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Comparative study of enzyme activity and heme reactivity in Drosophila melanogaster and Homo sapiens cystathionine beta-synthases

Cystathionine β-synthase (CBS) is the first and rate-limiting enzyme in the transsulfuration pathway, which is critical for eukaryotes to synthesize cysteine from methionine. CBS uses a coenzyme pyridoxal-5′-phosphate (PLP) for catalysis and S-adenosylmethionine regulates the activity of human CBS,...

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Detalhes bibliográficos
Main Authors: Su, Yang, Majtan, Tomas, Freeman, Katherine M., Linck, Rachel, Ponter, Sarah, Kraus, Jan P., Burstyn, Judith N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751582/
https://ncbi.nlm.nih.gov/pubmed/23002992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300615c
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