Identification of the feline foamy virus Bet domain essential for APOBEC3 counteraction

BACKGROUND: APOBEC3 (A3) proteins restrict viral replication by cytidine deamination of viral DNA genomes and impairing reverse transcription and integration. To escape this restriction, lentiviruses have evolved the viral infectivity factor (Vif), which binds A3 proteins and targets them for proteo...

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Main Authors: Lukic, Dragana Slavkovic, Hotz-Wagenblatt, Agnes, Lei, Janet, Räthe, Ann-Mareen, Mühle, Michael, Denner, Joachim, Münk, Carsten, Löchelt, Martin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751544/
https://ncbi.nlm.nih.gov/pubmed/23880220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-76
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