Identification of the feline foamy virus Bet domain essential for APOBEC3 counteraction

BACKGROUND: APOBEC3 (A3) proteins restrict viral replication by cytidine deamination of viral DNA genomes and impairing reverse transcription and integration. To escape this restriction, lentiviruses have evolved the viral infectivity factor (Vif), which binds A3 proteins and targets them for proteo...

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Detalhes bibliográficos
Main Authors: Lukic, Dragana Slavkovic, Hotz-Wagenblatt, Agnes, Lei, Janet, Räthe, Ann-Mareen, Mühle, Michael, Denner, Joachim, Münk, Carsten, Löchelt, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751544/
https://ncbi.nlm.nih.gov/pubmed/23880220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-76
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