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The antiretroviral activity of APOBEC3 is inhibited by the foamy virus accessory Bet protein

Genome hypermutation of different orthoretroviruses by cellular cytidine deaminases of the APOBEC3 family during reverse transcription has recently been observed. Lentiviruses like HIV-1 have acquired proteins preventing genome editing in the newly infected cell. Here we show that feline foamy virus...

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Bibliografski detalji
Glavni autori: Löchelt, Martin, Romen, Fabian, Bastone, Patrizia, Muckenfuss, Heide, Kirchner, Nadine, Kim, Yong-Boum, Truyen, Uwe, Rösler, Uwe, Battenberg, Marion, Saib, Ali, Flory, Egbert, Cichutek, Klaus, Münk, Carsten
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142374/
https://ncbi.nlm.nih.gov/pubmed/15911774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501445102
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