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The antiretroviral activity of APOBEC3 is inhibited by the foamy virus accessory Bet protein

Genome hypermutation of different orthoretroviruses by cellular cytidine deaminases of the APOBEC3 family during reverse transcription has recently been observed. Lentiviruses like HIV-1 have acquired proteins preventing genome editing in the newly infected cell. Here we show that feline foamy virus...

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Detalhes bibliográficos
Main Authors: Löchelt, Martin, Romen, Fabian, Bastone, Patrizia, Muckenfuss, Heide, Kirchner, Nadine, Kim, Yong-Boum, Truyen, Uwe, Rösler, Uwe, Battenberg, Marion, Saib, Ali, Flory, Egbert, Cichutek, Klaus, Münk, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142374/
https://ncbi.nlm.nih.gov/pubmed/15911774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501445102
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